Welcome to the very first issue of the openRxiv Re:Port newsletter! This newsletter will be a space where we share updates and highlight developments across bioRxiv and medRxiv and insights into how openRxiv is working to broaden access to scientific information and advance communication at the speed of science. Why the name Re:Port?Re:Port embodies the dynamic exchange of scientific knowledge - replying to and reporting on emerging research while serving as an open portal where discoveries flow freely, accelerating the journey from insight to impact.
Since the launch of bioRxiv and medRxiv at Cold Spring Harbor Laboratory, we've made significant progress in ensuring that preprints are trusted, accessible, and impactful. With bioRxiv and medRxiv now under the umbrella of the new independent and scientist-led, non-profit openRxiv, this is only the beginning. With the support of our community, we are committed to advancing independence, strengthening transparency, and expanding opportunities for researchers everywhere to share their work rapidly and openly.
I'm grateful and excited to serve as theinaugural CEOof openRxiv. As a scientist, I know firsthand the importance of rapid and transparent sharing of knowledge. As a leader, I've seen how openness and collaboration can transform entire fields and empower communities of researchers around the world. That's why I'm so excited to help continue building on the foundation we've established at openRxiv.
Through openRxiv Re:Port, we'll keep you informed about new initiatives, highlight the work of our partners and contributors, and provide ways to engage with openRxiv as we grow. Most importantly, it's an invitation to stay connected as we shape the future of scientific communication together.
Starting December 1, 2025, all new bioRxiv and medRxiv preprints will receive DOIs with openRxiv's unique prefix (10.64898), while existing preprints retain their original identifiers with no action required from authors or readers. The article details how preprint DOIs are structured to include submission dates, how they link to published journal versions, and how DOI records evolve to capture peer reviews, citations, and other scholarly activities over time. >>Read More
openRxiv hosted a satellite meeting during the Chan Zuckerberg Initiative's Open Science conference, bringing together scientists, funders, and nonprofit organizations to discuss the future of scientific communication. The event showcased organizations that are creating an interconnected network linking preprints with data repositories, peer review services, and verification tools to enhance research transparency and discoverability. >>Read More
Preprint mandates gather momentum The Howard Hughes Medical Institute has implemented a new policy requiring its scientists to post their research as preprints on nonprofit servers like bioRxiv and medRxiv. This move aligns HHMI with other funders already mandating preprint sharing and represents a significant step toward immediate, free access to biomedical research findings.>>Read More
Researchers can now publish their preprints and deposit datasets simultaneously through a new integration between bioRxiv and Dryad. This workflow reduces the traditional friction between rapid scientific communication and comprehensive data sharing, supporting more robust and transparent research practices. >> Read More
bioRxiv now enables authors to add standardized funding information directly to their preprints, automatically linking funder information from the Research Organization Registry for improved accuracy and searchability. The new feature allows researchers to update funding information on both new submissions and existing preprints, making it easier to track research support and enhance manuscript discoverability. >>Read More
Dr. Richard Sever and Dr. John Inglis have earned the prestigious 2025 Research Culture Award for contributions to improving the scientific system and changing the culture of scientific publishing, through the development of the first preprint servers for the life sciences and medicine. This honor recognizes the work of the co-founders, team and community of bioRxiv and medRxiv who brought preprints to the life sciences. >> Read More
Preprint Pulse
Community and Events
ASAPbio, a scientist-driven nonprofit working to drive open and innovative communication is the life science, announcedthat the Gates Foundation joined their Member Advisory Group. Keep an eye out for future ASAPbio community calls, while joining the ongoing conversation around preprints and open peer review by watching previous community calls. >>Join the conversation
Applications are open until December 8th to join the 2026 PREreview Champions Program. As a Champion, you would join a community of peers dedicated to building a more open, equitable, and collaborative future for all researchers. >> Apply here.
By the Numbers
bioRxiv: 306,297preprints in biological sciences, advancing sharing and discovery.
medRxiv: 74,411preprints in health sciences, advancing medical knowledge and public health.
Thank You For Advancing Open Science
We are grateful to our newest supporters for investing in the future of open science and for their commitment to breaking down barriers in the way research is shared worldwide.
Science has always been about sharing stories, long before peer review or paywalls ever existed. From Aristotle (384–322 BCE) teaching students in ancient Athens to the legendary Library of Alexandria (founded ~283 BCE) gathering scrolls from across civilizations, knowledge flowed freely through direct exchange and open access. During the Islamic Golden Age (8th–13th centuries), brilliant minds like Ibn al-Haytham (965–1040) in Cairo and Avicenna (980–1037) in Persia translated, expanded, and shared scientific ideas across continents, creating a global network of learning that would make today's preprint servers proud. This ancient spirit of rapid, barrier-free knowledge exchange ultimately inspired Henry Oldenburg to launch the Philosophical Transactions in 1665 London, proving that the drive to share discoveries instantly and openly isn't revolutionary at all - it's how science began.
Help Us Spread the Re:Port
Love what you're reading? Share openRxiv Re: Portwith your research community! Please forward this newsletter to colleagues, post it on social media, or simply tell a fellow scientist about it over coffee. The more voices we have in this conversation about open science, the stronger our collective impact becomes. After all, the best discoveries happen when knowledge flows freely, and that includes newsletters, too.
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